In fact nicotine and caffeine go together hand in hand as the two have more in common than we have initially thought for example nicotine and caffeine are both alkaloids that derived from plants both of them naturally stimulate dopamine production in the brain as they act as stimulants on the central nervous system. Caffeine and nicotine had large effect sizes on electroencephalogram eeg power however these effects were modulated by the eyes open versus closed condition the other drug and electrode site eeg effects of open versus closed eyes tended to be of the same size and direction as those of nicotine and caffeine. Chemically nicotine is very similar to caffeine and coffee is one of the most widely traded products in the world juul co founder james monsees told the mercury news in september 2018 while. Caffeine and nicotine are two of the most commonly abused drugs in various forms while coffee is the substance read beverage that is consumed by people as an energy drink that contains caffeine the most popular source of nicotine intake is cigarette both drugs have effects that are described differently by those who are used to them
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